Rars2 conditional Knockout mouse

Target

Gene symbol :

Rars2

NCBI gene ID :

109093

Gene full name :

Arginyl-tRNA synthetase 2, mitochondrial

Synonym :

—

Protein function

Protein name :

Arginyl-tRNA synthetase, mitochondrial

Catalyzes aminoacylation of tRNA^Arg in mitochondria

Expected phenotype

Knockouts show mitochondrial dysfunction and impaired development

Human disease relevance

Mutations cause pontocerebellar hypoplasia and encephalopathy

Model applications

Studied in mitochondrial translation and neurodevelopment

Keywords:

tRNA synthetase, Mitochondria, Translation, Neurology

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rars2

conditional Knockout mouse

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