Target

Gene symbol :  
Rnf138
NCBI gene ID :  
56515
Gene full name :  
Ring finger protein 138
Synonym :  
GID9, NARF

Protein function

Protein name :  
E3 ubiquitin-protein ligase RNF138
Ubiquitin ligase involved in DNA repair and Wnt signaling

Expected phenotype

Defective DNA damage response

Human disease relevance

Potential tumor suppressor and immune regulator

Model applications

Cancer, immune response, ubiquitin system

Keywords:

E3 ligase, DNA repair, Wnt signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rnf138

conditional Knockout mouse

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