Target

Gene symbol :  
Rnf7
NCBI gene ID :  
19823
Gene full name :  
Ring finger protein 7
Synonym :  
ROC2, SAG, Rbx2

Protein function

Protein name :  
RNF7
E3 ubiquitin ligase subunit involved in proteasomal degradation pathways

Expected phenotype

Cell cycle arrest, apoptosis dysregulation

Human disease relevance

Associated with cancer and neurodegeneration

Model applications

Ubiquitin–proteasome system models

Keywords:

E3 ligase, Proteasome, Cell cycle

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Rnf7

conditional Knockout mouse

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