Runx1t1 conditional Knockout mouse

Target

Gene symbol :

Runx1t1

NCBI gene ID :

12395

Gene full name :

Runt-related transcription factor 1, translocated to 1 (cyclin D-related)

Synonym :

ETO, MTG8

Protein function

Protein name :

RUNX1T1

Transcriptional corepressor interacting with RUNX1 in hematopoietic regulation.

Expected phenotype

Altered hematopoiesis

Human disease relevance

Translocation partner in AML t(8;21)

Model applications

Leukemia models, transcriptional repression

Keywords:

AML, Transcription corepressor, Hematopoiesis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Runx1t1

conditional Knockout mouse

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