Ryr1 conditional Knockout mouse

Target

Gene symbol :

Ryr1

NCBI gene ID :

20190

Gene full name :

Ryanodine receptor 1 (skeletal muscle)

Synonym :

RyR1, RYRα

Protein function

Protein name :

RYR1

Calcium release channel in the sarcoplasmic reticulum; controls skeletal muscle contraction

Expected phenotype

Malignant hyperthermia, muscle weakness

Human disease relevance

Mutations cause malignant hyperthermia and myopathies

Model applications

Muscular physiology and anesthesiology models

Keywords:

Calcium channel, Muscle, Myopathy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ryr1

conditional Knockout mouse

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