Setd1a conditional Knockout mouse

Target

Gene symbol :

Setd1a

NCBI gene ID :

233904

Gene full name :

SET domain containing 1A

Synonym :

KMT2F

Protein function

Protein name :

Histone-lysine N-methyltransferase SETD1A

H3K4 methyltransferase regulating chromatin and transcription

Expected phenotype

Heterozygous KO causes cognitive and behavioral deficits

Human disease relevance

Mutations linked to schizophrenia and intellectual disability

Model applications

Used in neurodevelopmental and epigenetic studies

Keywords:

Histone methylation, Epigenetics, Schizophrenia, Transcription regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Setd1a

conditional Knockout mouse

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