Target

Gene symbol :  
Sgms1
NCBI gene ID :  
208449
Gene full name :  
Sphingomyelin synthase 1
Synonym :  
SMSr, Sms1

Protein function

Protein name :  
Sphingomyelin synthase 1
Catalyzes synthesis of sphingomyelin from ceramide; involved in lipid homeostasis

Expected phenotype

Knockouts alter sphingolipid composition and immune cell function

Human disease relevance

Implicated in lipid metabolic disorders and inflammation

Model applications

Used in sphingolipid metabolism and immunology research

Keywords:

Sphingolipids, Ceramide, Membrane biology, Immunology

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Sgms1

conditional Knockout mouse

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