Smg9 conditional Knockout mouse

Target

Gene symbol :

Smg9

NCBI gene ID :

71997

Gene full name :

SMG9 nonsense mediated mRNA decay factor

Synonym :

SmgGDS-like

Protein function

Protein name :

Nonsense-mediated mRNA decay factor SMG9

Part of NMD complex; regulates surveillance and decay of faulty mRNAs

Expected phenotype

Knockout leads to developmental delay and heart malformations

Human disease relevance

Linked to SMG9-deficiency syndrome (intellectual disability, heart defects)

Model applications

Studied in RNA surveillance and congenital disorders

Keywords:

NMD, RNA decay, Heart development, SMG complex

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Smg9

conditional Knockout mouse

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