Smn1 conditional Knockout mouse

Target

Gene symbol :

Smn1

NCBI gene ID :

20595

Gene full name :

Survival motor neuron 1

Synonym :

Smn, SMA

Protein function

Protein name :

SMN

Essential for snRNP assembly and motor neuron survival.

Expected phenotype

Motor neuron loss, muscular atrophy

Human disease relevance

Mutations cause spinal muscular atrophy (SMA)

Model applications

Neuromuscular disease, RNA processing

Keywords:

SMA, snRNPs, Motor neuron

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Smn1

conditional Knockout mouse

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