Target

Gene symbol :  
Syt1
NCBI gene ID :  
20979
Gene full name :  
Synaptotagmin 1
Synonym :  
Synaptotagmin-1, SYT I

Protein function

Protein name :  
SYT1
Calcium sensor that mediates synaptic vesicle exocytosis in neurons

Expected phenotype

Neuromuscular transmission defects, seizures

Human disease relevance

Associated with epileptic encephalopathy and autism

Model applications

Synaptic transmission, epilepsy models

Keywords:

Calcium sensor, Neurotransmission

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Syt1

conditional Knockout mouse

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