Target

Gene symbol :  
Tap1
NCBI gene ID :  
21354
Gene full name :  
Transporter associated with antigen processing 1
Synonym :  
Antigen peptide transporter 1 (TAP1)

Protein function

Protein name :  
TAP1
ATP-binding cassette transporter involved in MHC I antigen presentation

Expected phenotype

Impaired antigen presentation, viral susceptibility

Human disease relevance

Linked to immune deficiencies and infectious disease susceptibility

Model applications

Immunology, viral infection models

Keywords:

Antigen processing, Immunity, MHC I

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Tap1

conditional Knockout mouse

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