Tcf7l2 conditional Knockout mouse

Target

Gene symbol :

Tcf7l2

NCBI gene ID :

21416

Gene full name :

Transcription factor 7-like 2

Synonym :

TCF4, TCF-4

Protein function

Protein name :

TCF7L2

Wnt pathway transcription factor; controls glucose metabolism and cell differentiation

Expected phenotype

Glucose intolerance, gut hypoplasia

Human disease relevance

Strong genetic association with type 2 diabetes

Model applications

Metabolic disease and Wnt pathway models

Keywords:

Wnt signaling, Metabolism, Diabetes

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Tcf7l2

conditional Knockout mouse

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