Timp1 conditional Knockout mouse

Target

Gene symbol :

Timp1

NCBI gene ID :

21857

Gene full name :

Tissue inhibitor of metalloproteinase 1

Synonym :

Timp, Clgi, EPA, TIMP-1

Protein function

Protein name :

TIMP1

Inhibits MMPs, regulates ECM composition and tissue remodeling

Expected phenotype

Impaired tissue repair, fibrosis

Human disease relevance

Implicated in fibrosis, cancer, and inflammation

Model applications

ECM modeling, cancer metastasis

Keywords:

MMP inhibitor, ECM, Tissue remodeling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Timp1

conditional Knockout mouse

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