Traf6 conditional Knockout mouse

Target

Gene symbol :

Traf6

NCBI gene ID :

22034

Gene full name :

TNF receptor-associated factor 6

Synonym :

E3 ubiquitin-protein ligase TRAF6

Protein function

Protein name :

TRAF6

E3 ligase in immune signaling pathways (NF-κB, IL-1, TLR)

Expected phenotype

Immunodeficiency, osteopetrosis

Human disease relevance

Associated with inflammation, bone, and neural disorders

Model applications

Immune signaling and bone development

Keywords:

Ubiquitin ligase, NF-κB, TLR signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Traf6

conditional Knockout mouse

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