Trim25 conditional Knockout mouse

Target

Gene symbol :

Trim25

NCBI gene ID :

217069

Gene full name :

Tripartite motif-containing 25

Synonym :

Efp

Protein function

Protein name :

E3 ubiquitin/ISG15 ligase TRIM25

E3 ubiquitin ligase; promotes RIG-I–mediated antiviral signaling and ISGylation

Expected phenotype

Knockouts impair antiviral immune responses

Human disease relevance

Implicated in innate immunity, breast cancer, and viral defense

Model applications

Studied in ubiquitination, interferon signaling, and antiviral pathways

Keywords:

Ubiquitin ligase, ISGylation, RIG-I, Antiviral, Immunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Trim25

conditional Knockout mouse

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