Target

Gene symbol :  
Unc45a
NCBI gene ID :  
101869
Gene full name :  
Unc-45 myosin chaperone A
Synonym :  
SMAP-1, Smap1

Protein function

Protein name :  
Protein unc-45 homolog A
Acts as a myosin chaperone; regulates cytoskeletal function and cell division

Expected phenotype

Knockouts show defective cell division, impaired motility

Human disease relevance

Associated with cholestasis and myopathy in humans

Model applications

Used in studies of cytoskeletal dynamics and motor protein biology

Keywords:

Myosin chaperone, Cytoskeleton, Cell division, Motility

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Unc45a

conditional Knockout mouse

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