Target

Gene symbol :  
Vgll4
NCBI gene ID :  
232334
Gene full name :  
Vestigial-like family member 4
Synonym :  
TDU

Protein function

Protein name :  
Vestigial-like protein 4
Transcriptional cofactor antagonizing YAP/TAZ signaling

Expected phenotype

KO leads to cardiac and vascular defects

Human disease relevance

Implicated in cancer suppression and organ size regulation

Model applications

Used in Hippo pathway and cancer biology studies

Keywords:

Hippo pathway, YAP/TAZ inhibition, Tumor suppressor, Transcription cofactor

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Vgll4

conditional Knockout mouse

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