Wnt16 conditional Knockout mouse

Target

Gene symbol :

Wnt16

NCBI gene ID :

93735

Gene full name :

Wingless-type MMTV integration site family member 16

Synonym :

E130309I19Rik

Protein function

Protein name :

WNT‑16

Secreted Wnt ligand regulating bone homeostasis and osteoblast differentiation

Expected phenotype

Knockout mice show reduced cortical bone thickness and increased fracture risk

Human disease relevance

Mutations cause osteoporosis‑pseudoglioma syndrome and bone fragility

Model applications

Used in skeletal development and osteoporosis research

Keywords:

Wnt ligand, Bone biology, Osteoporosis, Skeletal

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Wnt16

conditional Knockout mouse

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