Looking for a translatable model to assess human cGAS–targeting therapeutics?

Generate translatable efficacy data for your hcGAS-targeting therapeutics

The genO-hcGAS mouse model offers a unique platform to generate translatable efficacy data for therapeutics targeting hcGAS.

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Efficacy assessment of cGAS agonist using genO-hcGAS mice

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What sets our genO-hcGAS model apart?

Our models presents unique features:

• Physiological regulation and expression of human cGAS
• Fully functional mouse immune system
• Lack of expression of the murine target gene

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Discover our catalog of genO-hcGAS mouse models

Our humanized genO-hcGAS mouse model has been intercrossed to achieve higher predictability:

• genO-hcGAS/hSTING
• genO-hcGAS/hTrex