Atp1a3 conditional Knockout mouse

Target

Gene symbol :

Atp1a3

NCBI gene ID :

232975

Gene full name :

ATPase Na+/K+ transporting subunit alpha 3

Synonym :

Na⁺/K⁺-ATPase α3, Atna3

Protein function

Protein name :

Na+/K+-ATPase subunit alpha-3

Maintains ion gradients across plasma membranes in neurons

Expected phenotype

KO is neonatal lethal; heterozygotes show neurological deficits

Human disease relevance

Mutations cause rapid-onset dystonia-parkinsonism and AHC

Model applications

Used in neurophysiology and movement disorder models

Keywords:

Ion transport, Na+/K+ pump, Neurons, Dystonia, AHC

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atp1a3

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe