Atp1a3 conditional Knockout mouse

Target

Gene symbol :

Atp1a3

NCBI gene ID :

232975

Gene full name :

ATPase Na+/K+ transporting subunit alpha 3

Synonym :

Na⁺/K⁺-ATPase α3, Atna3

Protein function

Protein name :

Na+/K+-ATPase subunit alpha-3

Maintains ion gradients across plasma membranes in neurons

Expected phenotype

KO is neonatal lethal; heterozygotes show neurological deficits

Human disease relevance

Mutations cause rapid-onset dystonia-parkinsonism and AHC

Model applications

Used in neurophysiology and movement disorder models

Keywords:

Ion transport, Na+/K+ pump, Neurons, Dystonia, AHC

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atp1a3

conditional Knockout mouse

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