Atxn2 conditional Knockout mouse

Target

Gene symbol :

Atxn2

NCBI gene ID :

20239

Gene full name :

Ataxin 2

Synonym :

Ataxin-2, Spinocerebellar ataxia 2

Protein function

Protein name :

Ataxin-2

RNA-binding protein regulating translation and stress granules; modulates TDP-43 toxicity.

Expected phenotype

Neurodegeneration, motor defects

Human disease relevance

Implicated in spinocerebellar ataxia 2 (SCA2), ALS

Model applications

Neurodegeneration, RNA metabolism, motor neuron disease

Keywords:

SCA2, TDP-43, RNA granules, ALS

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atxn2

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe