Ccl22 conditional Knockout mouse

Target

Gene symbol :

Ccl22

NCBI gene ID :

20299

Gene full name :

Chemokine (C-C motif) ligand 22

Synonym :

MDC, Macrophage-derived chemokine

Protein function

Protein name :

CCL22

Chemokine recruiting CCR4+ T cells; regulates immune cell trafficking to inflamed or tumor tissue.

Expected phenotype

Altered T cell recruitment

Human disease relevance

Implicated in allergy, autoimmunity, and cancer tumor microenvironment

Model applications

Tumor immunology, inflammation models

Keywords:

Chemokine, Immune regulation, T cell

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ccl22

conditional Knockout mouse

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