Target

Gene symbol :  
Ccl22
NCBI gene ID :  
20299
Gene full name :  
Chemokine (C-C motif) ligand 22
Synonym :  
MDC, Macrophage-derived chemokine

Protein function

Protein name :  
CCL22
Chemokine recruiting CCR4+ T cells; regulates immune cell trafficking to inflamed or tumor tissue.

Expected phenotype

Altered T cell recruitment

Human disease relevance

Implicated in allergy, autoimmunity, and cancer tumor microenvironment

Model applications

Tumor immunology, inflammation models

Keywords:

Chemokine, Immune regulation, T cell

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
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Ccl22

conditional Knockout mouse

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