Target

Gene symbol :  
Cdc42
NCBI gene ID :  
12540
Gene full name :  
Cell division cycle 42
Synonym :  
G25K, CDC42Hs

Protein function

Protein name :  
CDC42
Small GTPase regulating actin cytoskeleton, polarity, and vesicle trafficking.

Expected phenotype

Cytoskeletal and polarity defects

Human disease relevance

Linked to cancer, neurodevelopmental syndromes

Model applications

Cell migration, vesicle trafficking, cell polarity

Keywords:

GTPase, Cytoskeleton, Rho family

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cdc42

conditional Knockout mouse

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