Target

Gene symbol :  
Cdc42
NCBI gene ID :  
12540
Gene full name :  
Cell division cycle 42
Synonym :  
G25K, CDC42Hs

Protein function

Protein name :  
CDC42
Small GTPase regulating actin cytoskeleton, polarity, and vesicle trafficking.

Expected phenotype

Cytoskeletal and polarity defects

Human disease relevance

Linked to cancer, neurodevelopmental syndromes

Model applications

Cell migration, vesicle trafficking, cell polarity

Keywords:

GTPase, Cytoskeleton, Rho family

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cdc42

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe