Clec9a conditional Knockout mouse

Target

Gene symbol :

Clec9a

NCBI gene ID :

232414

Gene full name :

C-type lectin domain family 9 member A

Synonym :

DNGR-1, CD370

Protein function

Protein name :

CLEC9A

Receptor on dendritic cells that binds dead cell debris for cross-presentation.

Expected phenotype

Defective cross-presentation, immune response

Human disease relevance

Relevant in cancer vaccine development

Model applications

Dendritic cell biology, antigen presentation

Keywords:

Cross-priming, DAMP sensing, Immunotherapy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Clec9a

conditional Knockout mouse

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