Clec9a conditional Knockout mouse

Target

Gene symbol :

Clec9a

NCBI gene ID :

232414

Gene full name :

C-type lectin domain family 9 member A

Synonym :

DNGR-1, CD370

Protein function

Protein name :

CLEC9A

Receptor on dendritic cells that binds dead cell debris for cross-presentation.

Expected phenotype

Defective cross-presentation, immune response

Human disease relevance

Relevant in cancer vaccine development

Model applications

Dendritic cell biology, antigen presentation

Keywords:

Cross-priming, DAMP sensing, Immunotherapy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Clec9a

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe