Cmtm6 conditional Knockout mouse

Target

Gene symbol :

Cmtm6

NCBI gene ID :

67213

Gene full name :

CKLF-like MARVEL transmembrane domain containing 6

Synonym :

CKLFSF6

Protein function

Protein name :

CMTM6

Stabilizes PD-L1 on cell surface, regulating T-cell immune checkpoints.

Expected phenotype

Enhanced T-cell activation in KO models

Human disease relevance

Key target in immune checkpoint blockade therapies

Model applications

Tumor immunity, checkpoint control

Keywords:

PD-L1, T-cell regulation, Immunotherapy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cmtm6

conditional Knockout mouse

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