Cmtm6 conditional Knockout mouse

Target

Gene symbol :

Cmtm6

NCBI gene ID :

67213

Gene full name :

CKLF-like MARVEL transmembrane domain containing 6

Synonym :

CKLFSF6

Protein function

Protein name :

CMTM6

Stabilizes PD-L1 on cell surface, regulating T-cell immune checkpoints.

Expected phenotype

Enhanced T-cell activation in KO models

Human disease relevance

Key target in immune checkpoint blockade therapies

Model applications

Tumor immunity, checkpoint control

Keywords:

PD-L1, T-cell regulation, Immunotherapy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cmtm6

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe