Target

Gene symbol :  
Comt
NCBI gene ID :  
12846
Gene full name :  
Catechol-O-methyltransferase
Synonym :  
Catechol-O-methyltransferase

Protein function

Protein name :  
COMT
Enzyme degrading catecholamines (e.g., dopamine); regulates neurotransmitter levels.

Expected phenotype

Altered stress response, anxiety-like behavior

Human disease relevance

Associated with schizophrenia, pain sensitivity

Model applications

CNS signaling, catecholamine regulation

Keywords:

Dopamine, Methylation, Neuromodulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Comt

conditional Knockout mouse

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