Target

Gene symbol :  
Comt
NCBI gene ID :  
12846
Gene full name :  
Catechol-O-methyltransferase
Synonym :  
Catechol-O-methyltransferase

Protein function

Protein name :  
COMT
Enzyme degrading catecholamines (e.g., dopamine); regulates neurotransmitter levels.

Expected phenotype

Altered stress response, anxiety-like behavior

Human disease relevance

Associated with schizophrenia, pain sensitivity

Model applications

CNS signaling, catecholamine regulation

Keywords:

Dopamine, Methylation, Neuromodulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Comt

conditional Knockout mouse

Get in touch about

Let us know how we can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe