Ell2 conditional Knockout mouse

Target

Gene symbol :

Ell2

NCBI gene ID :

192657

Gene full name :

Elongation factor for RNA polymerase II 2

Synonym :

—

Protein function

Protein name :

Elongation factor RNA polymerase II 2

Enhances transcription elongation; involved in immunoglobulin class switching

Expected phenotype

Knockouts impair B-cell differentiation and antibody production

Human disease relevance

Linked to multiple myeloma and immune dysfunction

Model applications

Used in transcription and immunology studies

Keywords:

Transcription elongation, RNA Pol II, B cells, Antibody production

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ell2

conditional Knockout mouse

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