Ell2 conditional Knockout mouse

Target

Gene symbol :

Ell2

NCBI gene ID :

192657

Gene full name :

Elongation factor for RNA polymerase II 2

Synonym :

—

Protein function

Protein name :

Elongation factor RNA polymerase II 2

Enhances transcription elongation; involved in immunoglobulin class switching

Expected phenotype

Knockouts impair B-cell differentiation and antibody production

Human disease relevance

Linked to multiple myeloma and immune dysfunction

Model applications

Used in transcription and immunology studies

Keywords:

Transcription elongation, RNA Pol II, B cells, Antibody production

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ell2

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe