Myl2 conditional Knockout mouse

Target

Gene symbol :

Myl2

NCBI gene ID :

17906

Gene full name :

Myosin, light polypeptide 2, regulatory, cardiac, slow

Synonym :

RLC-2, MLC-2v

Protein function

Protein name :

MYL2

Regulatory light chain of myosin in cardiac muscle; modulates contraction.

Expected phenotype

Embryonic lethality, cardiac malformations.

Human disease relevance

Mutations cause familial hypertrophic cardiomyopathy.

Model applications

Models for heart development and cardiomyopathy.

Keywords:

Cardiac muscle, Myosin regulation, Heart development

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Myl2

conditional Knockout mouse

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