Ndufs3 conditional Knockout mouse

Target

Gene symbol :

Ndufs3

NCBI gene ID :

68349

Gene full name :

NADH:ubiquinone oxidoreductase subunit S3

Synonym :

Ndufs3r, CI-30k

Protein function

Protein name :

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3

Core subunit of mitochondrial Complex I; involved in electron transport and oxidative phosphorylation

Expected phenotype

Mitochondrial dysfunction; embryonic lethality in homozygous knockouts

Human disease relevance

Associated with Leigh syndrome and mitochondrial complex I deficiency

Model applications

Used to study mitochondrial diseases and oxidative phosphorylation defects

Keywords:

Mitochondria, Complex I, Leigh syndrome, Oxidative phosphorylation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ndufs3

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe