Target

Gene symbol :  
Nolc1
NCBI gene ID :  
70769
Gene full name :  
Nucleolar and coiled-body phosphoprotein 1
Synonym :  
Nopp44/46

Protein function

Protein name :  
Nucleolar and coiled-body phosphoprotein 1
Nucleolar protein involved in rRNA synthesis and nucleolar structure

Expected phenotype

Essential gene; knockout causes early embryonic lethality

Human disease relevance

Involved in ribosome biogenesis and nucleolar stress responses

Model applications

Used in rRNA transcription and nucleolar assembly research

Keywords:

Nucleolus, rRNA synthesis, Ribosome biogenesis, RNA Pol I

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Nolc1

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe