Nolc1 conditional Knockout mouse

Target

Gene symbol :

Nolc1

NCBI gene ID :

70769

Gene full name :

Nucleolar and coiled-body phosphoprotein 1

Synonym :

Nopp44/46

Protein function

Protein name :

Nucleolar and coiled-body phosphoprotein 1

Nucleolar protein involved in rRNA synthesis and nucleolar structure

Expected phenotype

Essential gene; knockout causes early embryonic lethality

Human disease relevance

Involved in ribosome biogenesis and nucleolar stress responses

Model applications

Used in rRNA transcription and nucleolar assembly research

Keywords:

Nucleolus, rRNA synthesis, Ribosome biogenesis, RNA Pol I

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nolc1

conditional Knockout mouse

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