Pax5 conditional Knockout mouse

Target

Gene symbol :

Pax5

NCBI gene ID :

18507

Gene full name :

Paired box 5

Synonym :

EBB-1, Pax-5

Protein function

Protein name :

PAX5

Transcription factor essential for B-cell lineage commitment and development.

Expected phenotype

Impaired B-cell development, immune deficiencies.

Human disease relevance

Associated with B-cell lymphomas and leukemias.

Model applications

Studies on immune system development and hematological malignancies.

Keywords:

Transcription factor, B-cell development, Immunology

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Pax5

conditional Knockout mouse

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