Target

Gene symbol :  
Pfn1
NCBI gene ID :  
18643
Gene full name :  
Profilin 1
Synonym :  
Profilin 1, actin binding protein

Protein function

Protein name :  
PFN1
Actin-binding protein regulating cytoskeletal dynamics.

Expected phenotype

Impaired cell motility, developmental abnormalities.

Human disease relevance

Associated with amyotrophic lateral sclerosis (ALS).

Model applications

Research on cytoskeleton and neurodegenerative diseases.

Keywords:

Actin binding, Cytoskeleton, Neurodegeneration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Pfn1

conditional Knockout mouse

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