Ppp3cc conditional Knockout mouse

Target

Gene symbol :

Ppp3cc

NCBI gene ID :

19057

Gene full name :

Protein phosphatase 3 catalytic subunit gamma

Synonym :

Calcineurin A gamma, PP2B-A gamma

Protein function

Protein name :

PPP3CC

Calcium/calmodulin-dependent protein phosphatase involved in T-cell activation.

Expected phenotype

Impaired immune responses, altered T-cell function.

Human disease relevance

Associated with immunodeficiency disorders.

Model applications

Studies on immune signaling and T-cell activation.

Keywords:

Calcineurin, T-cell activation, Immunology

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Ppp3cc

conditional Knockout mouse

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