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Conditional Knockout mice
Psen2

Psen2 conditional Knockout mouse

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Target

Gene symbol :  
Psen2
NCBI gene ID :  
19165
Gene full name :  
Presenilin 2
Synonym :  
Presenilin 2

Protein function

Protein name :  
PSEN2
Component of gamma-secretase complex; cleaves APP and Notch receptors.

Expected phenotype

Amyloid processing defects, cognitive changes

Human disease relevance

Associated with familial Alzheimer's disease

Model applications

Alzheimer’s modeling, APP processing

Keywords:

Gamma-secretase, APP, Neurodegeneration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Psen2

conditional Knockout mouse

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hPD-1
hLAG3

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hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1
hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.