Psen2 conditional Knockout mouse

Target

Gene symbol :

Psen2

NCBI gene ID :

19165

Gene full name :

Presenilin 2

Synonym :

Presenilin 2

Protein function

Protein name :

PSEN2

Component of gamma-secretase complex; cleaves APP and Notch receptors.

Expected phenotype

Amyloid processing defects, cognitive changes

Human disease relevance

Associated with familial Alzheimer's disease

Model applications

Alzheimer’s modeling, APP processing

Keywords:

Gamma-secretase, APP, Neurodegeneration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Psen2

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe