Target

Gene symbol :  
Sh3pxd2a
NCBI gene ID :  
14218
Gene full name :  
SH3 and PX domains 2A
Synonym :  
Tks5, Fish

Protein function

Protein name :  
SH3PXD2A
Scaffold protein regulating podosome formation and cell invasion.

Expected phenotype

Reduced podosome formation, defective invasion

Human disease relevance

Involved in cancer metastasis

Model applications

Invasion biology, actin remodeling

Keywords:

Tks5, Podosome, Cell migration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • WoldWide delivery by professional breeders

Sh3pxd2a

conditional Knockout mouse

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