Sh3pxd2a conditional Knockout mouse

Target

Gene symbol :

Sh3pxd2a

NCBI gene ID :

14218

Gene full name :

SH3 and PX domains 2A

Synonym :

Tks5, Fish

Protein function

Protein name :

SH3PXD2A

Scaffold protein regulating podosome formation and cell invasion.

Expected phenotype

Reduced podosome formation, defective invasion

Human disease relevance

Involved in cancer metastasis

Model applications

Invasion biology, actin remodeling

Keywords:

Tks5, Podosome, Cell migration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Sh3pxd2a

conditional Knockout mouse

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