Aak1 conditional Knockout mouse

Target

Gene symbol :

Aak1

NCBI gene ID :

269774

Gene full name :

AP2 associated kinase 1

Synonym :

—

Protein function

Protein name :

AP2-associated protein kinase 1

Serine threonine kinase regulating clathrin-mediated endocytosis through phosphorylation of adaptor protein complexes

Expected phenotype

Altered endocytosis and receptor trafficking, effects on neuronal signaling reported in loss-of-function studies

Human disease relevance

Implicated in neurological disorders and viral entry pathways

Model applications

Endocytosis models, neuronal signaling studies

Keywords:

clathrin-mediated endocytosis, kinase, vesicle trafficking

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Aak1

conditional Knockout mouse

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