Abca4 conditional Knockout mouse

Target

Gene symbol :

Abca4

NCBI gene ID :

11304

Gene full name :

ATP binding cassette subfamily A member 4

Synonym :

Abcr

Protein function

Protein name :

ATP-binding cassette transporter A4

Retina-specific transporter involved in clearance of retinaldehyde derivatives from photoreceptor outer segments

Expected phenotype

Progressive retinal degeneration, lipofuscin accumulation, impaired visual function

Human disease relevance

Stargardt disease, cone-rod dystrophy, retinal degeneration

Model applications

Retinal disease models, vision research

Keywords:

retina, ABC transporter, photoreceptor degeneration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Abca4

conditional Knockout mouse

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