Ackr3 conditional Knockout mouse

Target

Gene symbol :

Ackr3

NCBI gene ID :

12778

Gene full name :

Atypical chemokine receptor 3

Synonym :

Cxcr7, Rdc1

Protein function

Protein name :

Atypical chemokine receptor 3

Scavenges chemokines such as CXCL12, regulates chemokine gradients independently of classical G protein signaling

Expected phenotype

Defects in cell migration, vascular and neural development when disrupted

Human disease relevance

Cancer progression, inflammation, cardiovascular and neurological disorders

Model applications

Immunology, cancer biology, chemokine signaling models

Keywords:

chemokine scavenging, CXCL12, cell migration

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ackr3

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe