Target

Gene symbol :  
Adam19
NCBI gene ID :  
11492
Gene full name :  
ADAM metallopeptidase domain 19
Synonym :  
Meltrin beta

Protein function

Protein name :  
ADAM19 protein
Metalloprotease involved in ectodomain shedding of membrane proteins, regulates developmental signaling pathways

Expected phenotype

Developmental defects affecting heart, nervous system, and craniofacial structures

Human disease relevance

Congenital heart disease, developmental disorders

Model applications

Developmental biology, protease function studies

Keywords:

metalloprotease, ectodomain shedding, development

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Adam19

conditional Knockout mouse

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