Target

Gene symbol :  
Adcy3
NCBI gene ID :  
104111
Gene full name :  
Adenylate cyclase 3
Synonym :  

Protein function

Protein name :  
Adenylate cyclase type 3
Catalyzes conversion of ATP to cAMP, plays a key role in GPCR signaling, especially in olfactory neurons and hypothalamic pathways

Expected phenotype

Knockout mice show anosmia, altered energy balance, obesity and metabolic dysregulation

Human disease relevance

Obesity, metabolic disorders, sensory deficits

Model applications

Metabolism models, GPCR signaling, sensory biology

Keywords:

cAMP signaling, metabolism, olfaction

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Adcy3

conditional Knockout mouse

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